Philip C Spinella Selected Research

Hemostatics (Antihemorrhagics)

1/2022	Correlation between Thrombin Generation, Standard Coagulation Assays, and Viscoelastic Assays for Hemostatic Assessment in Critically Ill Children.
1/2022	Consensus Statement: Hemostasis Trial Outcomes in Cardiac Surgery and Mechanical Support.
1/2021	Evidence-Based and Clinically Relevant Outcomes for Hemorrhage Control Trauma Trials.
1/2021	Recommended primary outcomes for clinical trials evaluating hemostatic blood products and agents in patients with bleeding: Proceedings of a National Heart Lung and Blood Institute and US Department of Defense Consensus Conference.
1/2020	Clinical controversies in anticoagulation monitoring and antithrombin supplementation for ECMO.
1/2019	Thromboelastography Variables, Immune Markers, and Endothelial Factors Associated With Shock and NPMODS in Children With Severe Sepsis.
1/2019	In silico model of the dilutional effects of conventional component therapy versus whole blood in the management of massively bleeding adult trauma patients.
4/2018	Blood transfusion management in the severely bleeding military patient.
1/2018	How do I implement a whole blood program for massively bleeding patients?
1/2018	The evolution of pediatric transfusion practice during combat operations 2001-2013.

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Philip C Spinella Research Topics

Disease

43	Hemorrhage 01/2022 - 02/2008
38	Wounds and Injuries (Trauma) 11/2022 - 01/2007
22	Critical Illness (Critically Ill) 05/2022 - 07/2004
20	Hemorrhagic Shock 01/2022 - 04/2009
13	Shock 01/2021 - 08/2010
5	Anemia 01/2018 - 08/2017
3	COVID-19 06/2022 - 01/2021
3	Thrombosis (Thrombus) 01/2022 - 01/2021
3	Venous Thrombosis (Deep-Vein Thrombosis) 01/2021 - 02/2013
3	Transfusion-Related Acute Lung Injury 12/2020 - 01/2018
3	Sepsis (Septicemia) 12/2020 - 01/2018
3	Multiple Organ Failure (MODS) 12/2019 - 09/2010
3	Traumatic Brain Injuries (Traumatic Brain Injury) 09/2017 - 03/2003
3	Hypotension (Low Blood Pressure) 01/2016 - 11/2008
2	Drug-Related Side Effects and Adverse Reactions 01/2022 - 01/2020
2	Body Weight (Weight, Body) 01/2022 - 01/2018
2	Infections 06/2021 - 01/2019
2	Heart Arrest (Cardiac Arrest) 01/2020 - 01/2013
2	Respiratory Distress Syndrome (Acute Respiratory Distress Syndrome) 01/2020 - 01/2020
2	Transfusion Reaction 01/2019 - 05/2014
2	Hypothermia 01/2013 - 11/2009
1	Human Influenza (Influenza) 06/2022
1	Disease Progression 05/2022
1	Thromboembolism 01/2022
1	Delirium 01/2022
1	Stroke (Strokes) 01/2022
1	Lymphopenia (Lymphocytopenia) 06/2021
1	Respiratory Insufficiency (Respiratory Failure) 01/2021
1	Hemostatic Disorders 01/2021
1	COVID-19 related pediatric multisystem inflammatory disease 01/2021
1	Lung Injury 07/2020
1	Hypoxia (Hypoxemia) 01/2020
1	Autoimmune Hemolytic Anemia (Cold Agglutinin Disease) 01/2020
1	Liver Diseases (Liver Disease) 01/2020
1	Hypovolemia 01/2020
1	Congenital Heart Defects (Congenital Heart Defect) 01/2019
1	Thrombocytopenia (Thrombopenia) 01/2019
1	Surgical Blood Loss 04/2018
1	Hemophilia A (Haemophilia) 01/2018
1	Septic Shock (Toxic Shock Syndrome) 01/2018
1	Brain Injuries (Brain Injury) 01/2018
1	Brain Edema (Cerebral Edema) 04/2016

Drug/Important Bio-Agent (IBA)

22	Hemostatics (Antihemorrhagics)IBA 01/2022 - 03/2009
6	Hemoglobins (Hemoglobin)IBA 01/2022 - 04/2009
6	Oxygen (Dioxygen)IBA 01/2020 - 01/2013
5	Tranexamic Acid (AMCA)FDA Link 01/2022 - 01/2017
5	Fibrinogen (Factor I)FDA Link 01/2021 - 02/2008
4	Crystalloid SolutionsIBA 01/2018 - 01/2010
3	Thrombin FDA Link 01/2022 - 01/2021
3	Colloids (Colloid)IBA 04/2016 - 01/2010
3	recombinant FVIIa (rFVIIa)FDA Link 08/2010 - 02/2008
3	S100 Calcium Binding Protein beta SubunitIBA 05/2004 - 03/2003
2	TESIBA 01/2022 - 01/2020
2	Enoxaparin (Lovenox)FDA LinkGeneric 01/2021 - 01/2021
2	Detergents (Detergent)IBA 01/2020 - 05/2017
2	SolventsIBA 01/2020 - 05/2017
2	Blood Coagulation Factors (Coagulation Factor)IBA 01/2020 - 11/2009
2	Lactic Acid (Lactate)FDA LinkGeneric 01/2019 - 01/2016
2	Interleukin-6 (Interleukin 6)IBA 01/2019 - 04/2015
2	Biomarkers (Surrogate Marker)IBA 01/2019 - 01/2017
2	AnticoagulantsIBA 01/2018 - 04/2009
2	Factor VIIa (Activated Factor VII)IBA 03/2009 - 02/2008
2	Blood Proteins (Serum Proteins)IBA 05/2004 - 03/2003
1	Aminocaproic Acid (6 Aminocaproic Acid)FDA LinkGeneric 01/2022
1	Citric Acid (Citrate)FDA LinkGeneric 01/2022
1	Antifibrinolytic Agents (Antifibrinolytics)IBA 01/2022
1	Famciclovir (Famvir)FDA LinkGeneric 06/2021
1	Antiviral Agents (Antivirals)IBA 06/2021
1	Acyclovir (Aciclovir)FDA LinkGeneric 06/2021
1	RNA-Directed DNA Polymerase (Reverse Transcriptase)IBA 01/2021
1	AT 61IBA 01/2021
1	Factor VIII (Coagulation Factor VIII)IBA 01/2021
1	AntibodiesIBA 12/2020
1	IronIBA 01/2020
1	CytokinesIBA 01/2020
1	Chimeric Antigen ReceptorsIBA 01/2019
1	Interleukin-10 (Interleukin 10)IBA 01/2019
1	SaltsIBA 01/2019
1	SolutionsIBA 01/2018

Therapy/Procedure

41	Resuscitation 01/2022 - 03/2009
17	Therapeutics 05/2022 - 07/2008
10	Platelet Transfusion (Blood Platelet Transfusions) 01/2020 - 02/2011
9	Critical Care (Surgical Intensive Care) 06/2022 - 09/2009
9	Erythrocyte Transfusion 12/2020 - 02/2008
7	Artificial Respiration (Mechanical Ventilation) 12/2020 - 07/2004
6	Blood Transfusion (Blood Transfusions) 11/2022 - 07/2008
6	Extracorporeal Membrane Oxygenation 01/2022 - 08/2008
5	Blood Component Removal (Apheresis) 01/2020 - 04/2009
3	Perioperative Period 01/2022 - 09/2010
3	Central Venous Catheters 01/2021 - 02/2013
2	Catheters 01/2021 - 01/2021
1	Length of Stay 06/2022
1	Heart-Assist Devices 01/2022
1	Hematopoietic Stem Cell Transplantation 06/2021
1	Positive-Pressure Respiration (Positive End-Expiratory Pressure) 01/2020
1	Mechanical Ventilators (Ventilator) 01/2020
1	Liver Transplantation 01/2020
1	Cardiopulmonary Bypass (Heart-Lung Bypass) 01/2019
1	Postoperative Care 04/2018
1	Immunomodulation 01/2017